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EPNOE Workshop Polysaccharides in Drug Delivery - On the Road to Innovation!
October 27-28, 2022
Rome, Italy

Invited lecture:
Thiolated Polysaccharides: From the Bench to Market
Prof. Dr. A. Bernkop-Schnürch
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Laboratory 2

 

 

 

Thiomer Technology


ThioMatrix’s drug delivery technologies are mainly based on thiolated polymeric excipients or designated thiomers. Due to the immobilization of thiol groups on already well-established polymeric excipients such as polyacrylates or chitosans the following features are strongly improved:

  • mucoadhesive properties more....

  • permeation enhancing effect more....

  • capability to provide a controlled drug release more....

  • enzyme inhibtory properties more....

  • in-situ gelling features more....

  • efflux pump inhibition more....

 


Self-Emulsifying Drug Delivery Systems

Thiomatrix is also specialized on the design and development of self-nanoemulsifying and self-microemulsifying drug delivery systems (SNEDDS; SMEDDS) collectively summarized as self-emulsifying drug delivery systems (SEDDS). In particular we develop SEDDS providing:

  • a protective effect towards a presystemic metabolism more....

  • high mucus permeating properties more....

  • high mucoadhesive properties more....

  • high spreading properties on the mucosa more....

  • permeation enhancing properties more....


Based on various in-house generated technologies we can incorporate also hydrophilic macromolecular drugs such as therapeutic peptides and DNA/RNA-based drugs in SEDDS.

 

  News

A. Bernkop-Schnürch, CSO ThioMatrix, was honored with the Gattefossé North America Award 2017
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ThioMatrix Hotline:
+43 512 890046
Mo-Th 9.00-17.00
and Fr 9.00-14.00


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