5th International Conference and Exhibition on Pharmaceutical Science and Technology
June 21-23, 2022
Bangkok, Thailand

Invited lecture:
Lipid-based Nanocarriers for Oral Delivery of Therapeutic Peptides: Hype or Hope?
Prof. Dr. A. Bernkop-Schnürch
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13th Global Drug Delivery & Formulation Summit
June 27-29, 2022
Berlin, Germany

Invited lecture:
Novel Nanotechnologies for Mucosal Delivery of Small Molecules and Biologics: Old Problems but New Solutions
Prof. Dr. A. Bernkop-Schnürch
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Solubility Enhancement Studies

ThioMatrix has great experience in formulation of poorly soluble APIs. In order to overcome solubility problems, ThioMatrix has developed a rational screening platform aimed at finding cost-effective and quick solutions to support such studies. After a solubility screening and cristallinity assessment the identified poor solubility of APIs can bee enhanced by:

• solidlid-state modifications such as salt formation, particle size reduction or solid-state stabilization of the amorphous state
  
  
• addition of co-solvents
  
  
• development of lipid based systems such as microemulsions
  
  
• formation of complexes such as with cyclodextrins
  
  
• addition of additives such as surfactants or polymer
  
  
• Sufficient solubility is a prerequisite for essential in vitro analyses such as permeation studies and subsequently the development of highly efficient drug delivery systems.

Sufficient solubility is a prerequisite for essential in vitro analyses such as permeation studies and subsequently the development of highly efficient drug delivery systems.

A. Bernkop-Schnürch, CSO ThioMatrix, was honored with the Gattefossé North America Award 2017
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